DESCRIPTION:
The use of the invention will make it possible to develop a method for the early diagnosis of tuberculosis. Immunization of animals, selective cultivation of microorganisms, obtaining polyclonal antisera, affinity purification of preparations of polyclonal antisera, heterogeneous enzyme-linked immunosorbent assay. The model makes it possible to develop a method for diagnosing tuberculosis.
ADVANTAGES:
-
- 2-20 times less time in comparison with analogs;
- safety;
- technical simplicity;
- selective accumulation of mycobacterial biomass without an intermediate stage of isolation of a pure culture of bacteria.
CHARACTERISTICS:
The method is developed on the basis of a vaccine strain, which is pretreated with a growth stimulant followed by its cultivation on a selective VKH medium.
PURPOSE:
The development is intended for the introduction of a safe and technically easy-to-implement method of obtaining immunogens from mycobacterium tuberculosis.
AREA:
Medicine and immunology.
RESULTS:
Provides consistent results.
READINESS:
Ready for implementation.
TRANSFER:
Sale of licenses. Collaborative industrialization.
NOVELTY:
1 patent of Ukraine.